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74


EQUINE VETERINARY EDUCATION / AE / FEBRUARY 2018


The descriptions of the ultrasound examinations of the cases in this report were very similar to the described case. Both horses in the previously described series responded well to conservative treatment. This filly appeared to cope well with the injury sustained, made steady progress over the first 48 h and subsequently went on to make a good recovery and was reported by an attending veterinarian to appear healthy at 18 months.


Antimicrobial use Cefquinome (Cobactan)2


is a fourth generation


cephalosporin and is listed under the WHO List of Critically Important Antimicrobials (CIA) (World Health Organisation 2012). The authors feel that the use of this CIA was justified by the desire to use an antimicrobial able to penetrate the blood-brain barrier. This was important in this case due to the presence of a severe head trauma in conjunction with an open skin wound. Cefquinome has been shown to penetrate the blood-brain barrier in other species (Pellegrini-Masini and Livesey 2006). Furthermore, in an abstract presented at the 2011 American College of Veterinary Internal Medicine Forum, cefquinome was found in the cerebrospinal fluid of normal horses 1 and 4 h after i.v. administration (Hollis et al. 2011). Since there are few drugs available with this property, the use of cefquinome was justified in this specific case.


Conclusion


In the described case, CT enabled a rapid accurate diagnosis with information on which to base management and possibly predict prognosis. Computed tomography should always be considered for cases of trauma involving the head or neck.


Authors’ declaration of interests No conflicts of interest have been declared.


Ethical animal research


The submitted case report describes a real case that was admitted to Rossdales Equine Hospital and Diagnostic Centre. The decision to publish the details of the case was made retrospectively and consequently did not influence the decision making, treatment, or outcome of the case. The highest standards of veterinary treatment and welfare were adhered to throughout the case and consequently there are no ethical considerations to review or approve.


Authorship


All authors had a constant, active and significant contribution to all aspects of preparation and submission of this case report. All authors approved the final version of the manuscript prior to submission.


Manufacturers' addresses


1Bimeda, Llangefni, Anglesey, Wales. 2MSD Animal Health, Walton, Milton Keynes, Buckinghamshire, UK. 3Zoetis UK Limited, Tadworth, Surrey, UK. 4Hameln Pharmaceuticals Ltd, Nexus, Gloucester, UK. 5Vetoquinol UK Ltd, Great Slade, Buckingham, UK. 6Siemens, Frimley, Surrey, UK.


7OsiriX DICOM viewer, osirix@osirix-viewer.com 8Logiq e, GE Medical Systems, Milwaukee, Wisconsin, USA. 9Boehringer Ingelheim Vetmedica GmbH, 55216 Ingelheim am Rhein, Germany.


10Merial Ltd., Duluth, Georgia, USA. References


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Feary, D.J., Magdesian, K.G., Aleman, M.A. and Rhodes, D.R. (2007) Traumatic brain injury in horses: 34 cases (1994-2004). J. Am. Vet. Med. Assoc. 231, 259-266.


Gellman, K.S. and Bertram, J.E.A. (2002) The equine nuchal ligament 1: structural and material properties. Vet. Comp. Orthop. Traumatol. 15, 1-6.


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Hollis, A.R., Duggan, V.E. and Corley, K.T.T. (2011) Does cefquinome penetrate the blood brain barrier in the normal horse? In: Research abstract program of the 2011 ACVIM Forum. J. Vet. Intern. Med. 25, 632-767.


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© 2016 EVJ Ltd


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