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446


EQUINE VETERINARY EDUCATION / AE / AUGUST 2019


Johnson, D.A. (2003) Review of esomeprazole in the treatment of acid disorders. Expert Opin. Pharmacother. 4, 253-264.


Lancaster-Smith, M.J., Jaderberg, M.E. and Jackson, D.A. (1991) Ranitidine in the treatment of non-steroidal anti-inflammatory drug associated gastric and duodenal ulcers. Gut 32, 252-255.


Lester, G.D., Smith, R.L. and Robertson, I.D. (2005) Effects of treatment with omeprazole or ranitidine on gastric squamous ulceration in racing Thoroughbreds. J. Am. Vet. Med. Ass. 227, 1636-1639.


Lind, T., Cederberg, C., Ekenved, G., Haglund, U. and Olbe, L. (1983) Effect of omeprazole–a gastric proton pump inhibitor–on pentagastrin stimulated acid secretion in man. Gut 24, 270-276.


Lorenzo-Figueras, M. and Merritt, A. (2002) Effects of exercise on gastric volume and pH in the proximal portion of the stomach of horses. Am. J. Vet. Res. 63, 1481-1487.


Luthersson, N., Nielsen, K.H., Harris, P. and Parkin, T.D.H. (2009a) The prevalence and anatomical distribution of equine gastric ulceration syndrome (EGUS) in 201 horses in Denmark. Equine Vet. J. 41, 619-624.


Luthersson, N., Nielsen, K.H., Harris, P. and Parkin, T.D.H. (2009b) Risk factors associated with equine gastric ulceration syndrome (EGUS) in 201 horses in Denmark. Equine Vet. J. 41, 625-630.


MacAllister, C.G., Sifferman, R.L., McClure, S.R., White, G.W., Vatistas, N.J., Holste, J.E., Ericcson, G.F. and Cox, J.L. (1999) Effects of omeprazole paste on healing of spontaneous gastric ulcers in horses and foals: a field trial. Equine Vet. J. 31, 77-80.


Malfertheiner, P., Chan, F.F.K.L., McColl, K.E.L. and Leung, W. (2009) Peptic-ulcer disease. Lancet 374, 1449-1461.


Merritt, A.M., Sanchez, L.C., Burrow, J.A., Church, M. and Ludzia, S. (2003) Effect of GastroGard and three compounded oral omeprazole preparations on 24 h intragastric pH in gastrically cannulated mature horses. Equine Vet. J. 35, 691-695.


Murray, M.J., Haven, M.L., Eichorn, E.S., Zhang, D., Eagleson, J. and Hickey, G.J. (1999) Effects of omeprazole on healing of naturally- occurring gastric ulcers in Thoroughbred racehorses. Equine Vet. J. 31, 425-429.


Murray, M.J., Nout, Y.S. and Ward, D.L. (2001) Endoscopic findings of the gastric antrum and pylorus in horses: 162 cases (1996–2000). J. Vet. Int. Med. 15, 401-406.


Sandin, A., Girma, K., Sj€ oholm, B., Lindholm, A. and Nilsson, G. (1998)


Effects of differently composed feeds and physical stress on plasma gastrin concentration in horses. Acta Vet. Scand. 39, 265-272.


Sandin, A., Andrews, F.M., Nadeau, J.A., Doherty, T.J. and Nillson, G. (1999) Effects of intramuscular omeprazole on gastric acid secretion in horses over a twenty-four hour period. Equine Vet. J. 31, 50-53.


Shin, J.M. and Sachs, G. (2008) Pharmacology of proton pump inhibitors. Curr. Gastroenterol. Rep. 10, 528-534.


Sykes, B.W., Sykes, K.M. and Hallowell, G.D. (2014a) A comparison between pre- and post-exercise administration of omeprazole in the treatment of EGUS: a randomised, blinded clinical trial. Equine Vet. J. 46, 422-426.


Sykes, B.W., Sykes, K.M. and Hallowell, G.D. (2014b) A comparison of two doses of omeprazole in the treatment of EGUS: a blinded, randomised, clinical trial. Equine Vet. J. 46, 416-421.


Sykes, B.W., Sykes, K.M. and Hallowell, G.D. (2014c) Administration of once daily trimethoprim-sulphadimidine does not improve healing of glandular gastric ulceration in horses receiving omeprazole: a randomised, blinded clinical trial. BMC Vet. Res. 10, 1-6.


Sykes, B.W., Hewetson, M., Hepburn, R.J., Luthersson, N. and Tamzali, Y. (2015a) European College of Equine Internal Medicine – Consensus Statement Equine Gastric Ulcer Syndrome (EGUS) in Adult Horses. J. Vet. Int. Med. 29, 1288-1299.


Sykes, B.W., Sykes, K.M. and Hallowell, G.D. (2015b) A comparison of three doses of omeprazole in the treatment of gastric ulceration in the horse: a randomised, blinded clinical trial. Equine Vet. J. 47, 285-290.


Sykes, B.W., Underwood, C., McGowan, C.M. and Mills, P.C. (2015c) The effect of feeding on the pharmacokinetic variables of two commercially available formulations of omeprazole. J. Vet. Pharm. Ther. 38, 500-503.


Sykes, B.W., Underwood, C., McGowan, C. and Mills, P. (2015d) Pharmacokinetics of intravenous, plain oral and enteric-coated oral omeprazole in the horse. J. Vet. Pharm. Ther. 38, 130-136.


Sykes, B.W., Underwood, C., McGowan, C. and Mills, P. (2016) Pharmacokinetics and bioavailability of five commercially available formulations of omeprazole. J. Vet. Pharm. Ther. 39, 78- 83.


Sykes, B., Kathawala, K., Song, Y., Garg, S., Page, S.W., Underwood, C. and Mills, P.C. (2017a) Preliminary investigations into a novel, long- acting, injectable, intramuscular formulation of omeprazole in the horse. Equine Vet. J. 49, 795-801.


Sykes, B.W., Underwood, C., Greer, R., McGowan, C.M. and Mills, P.C. (2017b) The effects of diet and dose on the pharmacodynamics of omeprazole in the horse. Equine Vet. J. 49, 525-531.


Sykes, B.W., Underwood, C., McGowan, C.M. and Mills, P.C. (2017c) The effects of dose and diet on the pharmacokinetics of omeprazole in the horse. J. Vet. Pharm. Ther. 40, 172-178.


Sykes, B.W., Underwood, C. and Mills, P.C. (2017d) The effect of dose and diet on the pharmacodynamics of oral esomeprazole in the horse. Equine Vet. J. 49, 637-642.


Varley, G., Bowen, I.M., Nicholls, V., Habershon-Butcher, J.L. and Hallowell, G.D. (2016) Misoprostol is superior to combined omeprazole and sucralfate for healing glandular gastric lesions in horses with clinical disease [abstract]. J. Vet. Int. Med. 1544.


Vatistas, N.J., Sifferman, R.L. and Holste, J. (1999) Induction and maintenance of gastric ulceration in horses in simulated race training. Equine Vet. J. 31, 40-44.


Videla, R., Sommardahl, C.S., Elliott, S.B., Vasili, A. and Andrews, F.M. (2011) Effects of intravenously administered esomeprazole sodium on gastric juice pH in adult female horses. J. Vet. Int. Med. 25, 558- 562.


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