search.noResults

search.searching

dataCollection.invalidEmail
note.createNoteMessage

search.noResults

search.searching

orderForm.title

orderForm.productCode
orderForm.description
orderForm.quantity
orderForm.itemPrice
orderForm.price
orderForm.totalPrice
orderForm.deliveryDetails.billingAddress
orderForm.deliveryDetails.deliveryAddress
orderForm.noItems
570


EQUINE VETERINARY EDUCATION / AE / NOVEMBER 2020


Nephrosplenic entrapment may be corrected using


surgical or non-surgical methods and has an excellent prognosis for survival. Correction of the entrapment via exploratory celiotomy may be challenging in certain cases and is hampered by marked splenic enlargement. Direct intra-splenic injection of phenylephrine is a novel method of reducing the size of the spleen, which facilitated correction of nephrosplenic entrapment in a recently reported clinical case (Loomes and Anderson 2020). The direct intra-splenic phenylephrine injection technique warrants further investigation to determine safety and the lowest efficacious dose.


Authors’ declaration of interests No conflicts of interest have been declared.


Ethical animal research Not applicable to this clinical commentary.


Authorship


Both authors equally contributed to manuscript preparation and both approved the final version.


References Baker, W.T., Frederick, J., Gigu


Epstein, K.L. and Parente, E.J. (2006) Laparoscopic obliteration of the nephrosplenic space using polypropylene mesh in five horses. Vet. Surg. 35, 431-437.


Farstvedt, E. and Hendrickson, D. (2005) Laparoscopic closure of the nephrosplenic space for prevention of recurrent nephrosplenic entrapment of the ascending colon. Vet. Surg. 34, 642-645.


Frederick, J., Gigu ere, S., Butterworth, K., Pellegrini-Masini, A., Casas-


Dolz, R. and Turpin, M.M. (2010) Severe phenylephrine-associated hemorrhage in five aged horses. J. Am. Vet. Med. Assoc. 237, 830- 834.


Fultz, L.E., Peloso, J.G., Gigu ere, S. and Adams, A.R. (2013) Comparison


of phenylephrine administration and exercise versus phenylephrine administration and a rolling procedure for the correction of nephrosplenic entrapment of the large colon in horses: 88 cases (2004-2010). J. Am. Vet. Med. Assoc. 242, 1146-1151.


Hardy, J., Bednarski, R.M. and Biller, D.S. (1994) Effects of phenylephrine on hemodynamics and splenic dimensions in horses. Am. J. Vet. Res. 55, 1570-1578.


Hardy, J., Minton, M., Robertson, J.T., Beard, W.L. and Beard, L.A. (2000) Nephrosplenic entrapment in the horse: a retrospective study of 174 cases. Equine Vet. J. 32, Suppl. 32 95-97.


Hunt, R.J. and Spirito, M.A. (1995) Ventral midline colopexy as a prevention of large colon volvulus. Proc. Am. Assoc. Equine Pract. 41, 202-203.


Krueger, C.R. and Klohnen, A. (2013) Surgical correction of nephrosplenic entrapment of the large colon in 3 horses via standing left flank laparotomy. Vet. Surg. 44, 392-397.


Le Jeune, S. and Whitcomb, M.B. (2014) Ultrasound of the equine acute abdomen. Vet. Clin. Equine. 30, 353-381.


ere, S., Lynch, T.M., Lehmkuhl, H.D. and


Slone, D.E. (2011) Re-evaluation of the effect of phenylephrine on resolution of nephrosplenic entrapment by the rolling procedure in 87 horses. Vet. Surg. 40, 825-829.


Benedict, C.R. and Rose, J.A. (1992) Arterial norepinephrine changes in patients with septic shock. Circ. Shock. 38, 165-172.


Bertone, A.L., Toofanian, F. and Stashak, T.S. (1989) Digestion, fecal, and blood variables associated with extensive large colon resection in the horse. Am. J. Vet. Res. 50, 253-258.


Busschers, E., Southwood, L.L. and Parente, E.J. (2007) Laparoscopic diagnosis and correction of a nephrosplenic entrapment of the large colon in a horse. Equine Vet. Educ. 19, 60-63.


Compostella, F., Roberts, V.L.H. and Tremaine, W.H. (2012) Haemoabdomen and colitis following a colon displacement in a 9-year-old Thoroughbred mare. Equine Vet. Educ. 24, 563-568.


Dancker, C., Hopster, K., Rohn, K. and Kastner, S.B. (2018) Effects of dobutamine, dopamine, phenylephrine and noradrenaline on systemic haemodynamics and intestinal perfusion in isoflurane anaesthetised horses. Equine Vet. J. 50, 104-110.


Loomes, K. and Anderson, J. (2020) Intra-splenic administration of phenylephrine in a horse to induce splenic contraction in a case of nephrosplenic entrapment of the large colon non-responsive to intravenous phenylephrine administration. Equine Vet. Educ. 32, 567.


Munoz, J. and Bussy, C. (2013) Standing hand-assisted laparoscopic treatment of left dorsal displacement of the large colon and closure of the nephrosplenic space. Vet. Surg. 42, 595-599.


Nelson, B.B., Ruple-Czerniak, A.A., Hendrickson, D.A. and Hackett, E.S. (2016) Laparoscopic closure of the nephrosplenic space in horses with nephrosplenic colonic entrapment: factors associated with survival and colic recurrence. Vet. Surg. 45, O60-O69.


Ohta, M., Kurimoto, S., Ishikawa, Y., Tokushige, H., Mae, N., Nagata, S.I. and Mamada, M. (2013) Cardiovascular effects of dobutamine and phenylephrine infusion in sevoflurane-anesthetized thoroughbred horses. J. Vet. Med. Sci. 75, 1443-1448.


Scharner, D., Rotting, A., Gerlach, K., Rasch, K. and Freeman, D.E. (2002) Ultrasonography of the abdomen in the horse with colic. Clin. Tech. Equine. Pract. 1, 118-124.


Southwood, L.L. (2019) Large colon. In: Equine Surgery, 5th edn., Eds: J. Auer, J. Stick, J. Kummerle and T. Prange. Elsevier, St Louis.pp591-621.


© 2019 EVJ Ltd


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62  |  Page 63  |  Page 64  |  Page 65  |  Page 66  |  Page 67  |  Page 68  |  Page 69  |  Page 70  |  Page 71  |  Page 72  |  Page 73  |  Page 74  |  Page 75  |  Page 76  |  Page 77  |  Page 78  |  Page 79  |  Page 80  |  Page 81  |  Page 82  |  Page 83  |  Page 84  |  Page 85  |  Page 86  |  Page 87  |  Page 88