SPORTS MEDICINE AND REHABILITATION
65. Nagy I, Woolf CJ. Lignocaine selectively reduces C fibre– evoked neuronal activity in rat spinal cord in dtro by de- creasing N-methyl-D-aspartate and neurokinin. Pain 1996;64:59–70.
66. Robertson SA, Sanchez LC, Merritt AM, et al. Effect of systemic lidocaine on visceral and somatic nociception in conscious horses. Equine Vet J 2010;37:122–127.
67. Doherty TJ, Seddighi MR. Local anesthetics as pain ther- apy in horses. Vet Clin North Am Equine Pract 2010;26: 533–549.
68. Dern K, Watts M, Werle B, et al. Effect of delayed digital hypothermia on lamellar inflammatory signaling in the oli- gofructose laminitis model. J Vet Intern Med 2017;31:575– 581.
69. HollmannMW,Durieux ME, Fisher DM. Local anesthetics and the inflammatory response: a new therapeutic indica- tion? Anesthesiology 2000;93:858–875. ¨bbeler FJ, Ka
70. So ¨stner SB. Effects of transdermal lidocaine
or lidocaine with prilocaine or tetracaine on mechanical superficial sensation and nociceptive thermal thresholds in horses. Vet Anaesth Analg 2018;45:227–233.
71. Zarucco L, Driessen B, Scandella M, et al. Continuous perineural block of the palmar nerves: A new technique for pain relief in the distal equine forelimb. Clin Tech Equine Pract 2007;6:154–164.
72. Broome CB, Burnikel B. Novel strategies to improve early outcomes following total knee arthroplasty: A case control study of intra articular injection versus femoral nerve block. Int Orthop 2014;38:2087–2089.
73. Rice D, Heil JW, Biernat L. Pharmacokinetic profile and tolerability of liposomal bupivacaine following a repeated dose via local subcutaneous infiltration in healthy volun- teers. Clin Drug Investig 2017;37:249–257.
74. Lascelles BDX, Rausch-Derra LC, Wofford JA, et al. Pilot, randomized, placebo-controlled clinical field study to evalu- ate the effectiveness of bupivacaine liposome injectable sus- pension for the provision of post-surgical analgesia in dogs undergoing stifle surgery. BMC Vet Res 2016;12:1–10.
75. Knych HK, Mama KR, Moore CE, et al. Plasma and syno- vial fluid concentrations and cartilage toxicity of bupiva- caine following intra-articular administration of a liposomal formulation to horses. Equine Vet J 2019;51:408–414.
76. Griffenhagen G, Pezzanite L, Hendrickson D, et al. Lipo- somal encapsulated bupivacaine provides longer duration analgesia than bupivacaine HCl when administered as an abaxial sesamoid block in horses. Vet Anaesth Analg 2019; 46:831.e6–831.e7.
77. Taylor PM, Senior M. Update in advances in pain manage- ment for the equine practitioner. Equine Vet Educ 2019; 31:340–342.
78. Davis JL, Posner LP, Elce Y. Gabapentin for the treatment of neuropathic pain in a pregnant horse. J Am Vet Med Assoc 2007;231:755–758.
79. Taylor CP. The biology and pharmacology of calcium chan- nel alpha2-delta proteins. Drug Rev 2004;10:183–188.
80. Caldwell FJ, Taintor J, Waguespack RW, et al. Effect of PO administered gabapentin on chronic lameness in horses. J Equine Vet Sci 2015;35:536–540.
81. Guedes AGP, Morisseau C, Sole A, et al. Use of a soluble epoxide hydrolase inhibitor as an adjunct analgesic in a horse with laminitis. Vet Anaesth Analg 2013;40:440–448.
82. Readford PK, Lester GD, Secombe CJ. Temporohyoid os- teoarthropathy in two young horses. Aust Vet J 2013;91: 209–212.
83. Terry R, McDonnell SM, van Eps AW, et al. Pharmacoki- netic profile and behavioral effects of gabapentin in the horse. J Vet Pharmacol Ther 2010;33:485–494.
84. Gold JR, Grubb TL, Green S, et al. Plasma disposition of gabapentin after the intragastric administration of escalat- ing doses to adult horses. J Vet Intern Med 2020;34:933– 940.
85. Sysel AM, Pleasant RS, Jacobson JD, et al. Efficacy of an epidural combination of morphine and detomidine in allevi-
ating experimentally induced hindlimb lameness in horses. Vet Surg 1996;25:511–518.
86. Goodrich LR, Nixon AJ, Fubini SL, et al. Epidural mor- phine and detomidine decreases postoperative hindlimb lameness in horses after bilateral stifle arthroscopy. Vet Surg 2002;31:232–239.
87. Freitas GC, Carregaro AB, Gehrcke MI, et al. Epidural analgesia with morphine or buprenorphine in ponies with lipopolysaccharide (LPS)-induced carpal synovitis. Can J Vet Res 2011;75:141–146.
88. Carmona JU, Go ´mez WA, Lo ´pez C. Could platelet-rich
plasma be a clinical treatment for horses with laminitis? J Equine Vet Sci 2018;61:46–57.
89. Keen JA, Hillier C, McGorum BC, et al. Endothelin-medi- ated contraction of equine laminar veins. Equine Vet J 2008;40:488–492.
90. Katwa LC, Johnson PJ, Ganjam VK, et al. Expression of endothelin in equine laminitis. Equine Vet J 1999;31:243– 247.
91. Ingle-Fehr JE, Baxter GM. The effect of oral isoxsuprine and pentoxifylline on digital and laminar blood flow in healthy horses. Vet Surg 1999;28:154–160.
92. Kabbesh N, Gogny M, Chatagnon G, et al. Vasodilatory effect of pentoxifylline in isolated equine digital veins. Vet J 2012;192:368–373.
93. Kaye AD, Ibrahim IN, Kadowitz PJ, et al. Analysis of response to pentoxifylline in the pulmonary vascular bed of the cat. Crit Care Med 1996;24:263–267.
94. Crisman MV, Wilcke JR, Correll LS, et al. Pharmacoki- netic disposition of intravenous and oral pentoxifylline in horses. J Vet Pharmacol Ther 1993;16:23–31.
95. Liska DA, Akucewich LH, Marsella R, et al. Pharmacoki- netics of pentoxifylline and its 5-hydroxyhexyl metabolite after oral and intravenous administration of pentoxifylline to healthy adult horses. Am J Vet Res 2006;67:1621–1627.
96. Harkins JD, Mundy GD, Stanley S, et al. Character and duration of pharmacological effects of intravenous isoxsu- prine. Equine Vet J 1996;28:320–326.
97. Lopez HS, Hoyos Sepulveda ML, Brumbaugh G. Pharma- cologic and alternative therapies for the horse with chronic laminitis. Vet Clin North Am Equine Pract 1999;15:495– 516.
98. Turner AS, Tucker CM. The evaluation of isoxsuprine hy- drochloride for the treatment of navicular disease: A double blind study. Equine Vet J 1989;21:338–341.
99. Walker M, Geiser DR. Effects of acepromazine on the he- modynamics of the equine metatarsal artery, as determined by two-dimensional real-time and pulsed doppler ultra- sonography. Am J Vet Res 1986;47:1075–1078.
100. Hunt RJ, Brandon CI, McCann ME. Effects of acetyl- promazine, xylazine, and vertical load on digital arterial blood flow in horses. Am J Vet Res 1994;55:375–378.
101. Adair HS, Goble DO, Shires GMH. Evaluation of laser doppler flowmetry for measuring coronary band and lami- nar microcirculatory blood flow in clinically normal horses. Am J Vet Res 1994;55:445–449.
102. Inan M, Bakar E, Cerkezkayabekir A, et al. Mesenchymal stem cells increase antioxidant capacity in intestinal isch- emia/reperfusion damage. J Pediatr Surg 2017;52:1196-
103. Gu W, Hong X, Potter C, et al. Mesenchymal stem cells and vascular regeneration. Microcirculation 2017;24:1–15.
104. Prockop DJ, Oh JY. Mesenchymal stem/stromal cells (MSCs): Role as guardians of inflammation. Mol Ther 2012;20:14–20.
105. Angelone M, Conti V, Biacca C, et al. The contribution of adipose tissue-derived mesenchymal stem cells and platelet- rich plasma to the treatment of chronic equine laminitis: A proof of concept. Int J Mol Sci 2017;18:1–17.
106. Morrison S. Chronic laminitis: Foot management. Vet Clin North Am Equine Pract 2010;26:425–446.
107. Murakami M. Lipid mediators in life science. Exp Anim 2011;60:7–20.
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