with broad ranges in eNAD/EDM 1.78 ng/ml (95% CI 1.5–2.28; range 0.07–137.8 ng/ml) and CVCM-affected horses was 3.07 ng/ml (95% CI 1.15–29.9; range 0.20– 109.3 ng/ml). There was no effect of sex on serum or CSF pNfH levels; however, age was a significant vari- able among neurologically normal, eNAD/EDM, and CVCM groups.
4. Discussion
Serum pNfH of 1 ng/ml is supportive of eNAD/EDM (P 0.01). CSF pNfH of 3 ng/ml is supportive of either eNAD/EDM or CVCM (P 0.0001). Values below these levels do not rule out neurologic disease.
MEDICINE: NON-INFECTIOUS DISEASES Acknowledgments
Declaration of Ethics The Authors have adhered to the Principles of Vet- erinary Medical Ethics of the AVMA.
Conflict of Interest The Authors have no conflicts of interest.
