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the time of writing, further validation of the test is required in a population of clinical cases before use of the test can be recommended.
Summary
Disease of the squamous mucosa (ESGUS) and disease of the glandular mucosa (EGGUS) are distinct disease entities and should be viewed as such. Importantly, knowledge of one (i.e. ESGUS) cannot be directly extrapolated to the other (i.e. EGGUS). Instead, information such as prevalence, risk factors, treatment and prevention need to be specifically collected on each syndrome. Despite the appeal of alternative means of diagnosis they
remain largely unvalidated and gastroscopy remains the diagnostic test of choice, not just for its ability to confirm the presence or absence of disease but for its ability to distinguish ESGUS from EGGUS and assess the severity of disease. A thorough examination of the stomach is relatively easy to perform with the correct equipment, case preparation and operator expertise.
Authors’ declaration of interests
The authors do not have any conflicts of interest, financial or otherwise, that could reasonably be expected to influence the content of this article.
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