Ceftiofur sodium administration via RLP achieved adequate plasma concentrations for 12 hours. Adequate soft tissue concentrations were achieved for 24 hours but bone concentrations were not adequate beyond the initial perfusion time. Fur- ther research is needed to understand ceftio- fur sodium administration via RLP in disease states.
Acknowledgments
Declaration of Ethics The Authors declare that they have adhered to the Principles of Veterinary Medical Ethics of the AVMA.
Conflict of Interest This study was funded by Zoetis.