OST RESPONSES TO ERTUGLIFLOZIN
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FIGURE 1 Individual horse insulin responses to the oral sugar test in 10 horses, prior to and after 4 days of treatment with ertugliflozin at 0.05 mg/mg per os once daily. [Correction added on 6 December 2023, after first online publication: Figure 1 was corrected in this version.]
there was no statistically significant improvement in lameness in the 10 cases after 4 days of treatment. This suggests that the speed of im- provement in lameness likely varies between horses and is potentially due to individual factors such as previous episodes of laminitis, genet- ics, age, body weight and the degree of pre-existing lamellar damage
(Bertin & de Laat, 2017 ). Whilst 4 days of treatment was sufficient to demonstrate a reduction in insulin response, a longer follow-up might be more suitable to assess the effect of treatment on lameness grade. The findings of the current study are also consistent with those of a previous study, which demonstrated that three doses of
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