HIGHLIGHTS OF RECENT CLINICALLY RELEVANT PAPERS
sensor- evaluated equine lameness database. Cases were catego- rised by lameness location to the limb(s), diagnosis and the ratio
of the amplitude of forelimb to hindlimb lameness (Fore a /Hind a ). Differences in the numbers of ipsilateral impact and ipsilateral push- off cases in these categories were analysed with chi- square tests, effect sizes and odds ratios. In total, 49 ipsilateral impact and 36 ipsilateral push- off cases met the criteria for consistency, agnosis.
low variability and definitive di- Ipsilateral impact cases were more likely than ipsilateral
push- off cases to have forelimb- only lameness causes when Fore a / Hind a was >1 (OR = 43, 95% CI = 2.3–798). Ipsilateral push- off cases were more likely than ipsilateral impact cases to have hindlimb- only
causes when Fore a /Hind a was >1.0 (OR = 20, 95% CI = 2.2–200) and < 1.0 (OR = 14, 95% CI = 2.9–66.7). Compared with ipsilateral impact,
ipsilateral push- off cases were more frequently diagnosed with ten- don, suspensory ligament or high- motion joint disorders in hind- limbs (OR = 3.6, 95% CI = 1.1–12.3) and less with unknown causes (OR = 13.2, 95% CI = 3.2–75.2). In ipsilateral impact cases, positive forelimb regional anaesthesia often reduced hindlimb lameness, whereas in ipsilateral push- off cases, positive hindlimb regional an- aesthesia typically lessened forelimb lameness.
FREESTYLE LIBRE GLUCOSE MONITORING IN HORSES
This study by Rafael Françoso and co- workers in Brazil evaluated the feasibility of using the FreeStyle Libre (a continuous glucose monitoring system [CGMS]) for instantaneous continuous monitoring of interstitial glucose in adult horses and examined the applicability and accuracy of this system in horses submitted to combined glucose- insulin test (CGIT) . Ten healthy stallions were assigned to one of two groups based
on their body condition scores (BCS). Group 1 (G1, n = 5) consisted of nonobese horses with a BCS of 5 or 6, while Group 2 (G2, n = 5) con- sisted of obese horses with a BCS of 7 or higher. A CGMS sensor was attached to the dorsolateral aspect of the proximal one third of each horse ' s neck. Laboratory blood glucose measurements and CGMS in- terstitial glucose readings were compared at different time points for up to 7 days after sensor fixation. Obese horses were also submitted to CGIT on Day 4. Laboratory measurements and CGMS readings were analysed
using a 2 × 2 factorial statistical model with repeated measures over time. This analysis assessed the effects of the test (factor 1), group (factor 2) and their interactions (test × group, test × time, and group × time). Pearson ' s correlation analysis was applied to blood glucose values. Mean comparisons were conducted using the t - test,
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and agreement between techniques was assessed via the Bland– Altman method, with a 95% confidence interval. A comparative analysis of glucose measurements obtained in G1
and G2 horses using the CGMS, and enzymatic methods revealed significant group × time interactions ( p < 0.001) and time effects ( p < 0.001). No interactions were detected between group ( p = 0.45), test ( p = 0.62), group and test ( p = 0.28) or time and test ( p = 0.92). In G1 and G2, tests were significantly correlated ( r = 0.84 and p = 0.00) at all time points (T0–T5). Agreement between the glucose values obtained using different methods was excellent despite a small time delay in CGMS detection of rapid changes in blood glucose. The authors concluded that the CGMS can be used for indirect
assessment of glycaemic status (i.e. based on interstitial glucose measurements) in nonobese and obese adult horses submitted to CGIT.
Sue Wright
EVE Editorial Office Email:
sue@evj.co.uk
ORCID Sue Wright
https://orcid.org/0000-0002-5513-8571
REFERENCES
Françoso , R. , Baccarin , R.Y. , de Siqueira , R.F. & Belli , C.B. ( 2024 ) Use of FreeStyle libre for continuous glucose monitoring in adult horses . Journal of Veterinary Emergency and Critical Care (san Antonio). , 34 ( 2 ), 123 – 130 . Available from: https:// doi. org/ 10. 1111/ vec. 13367
Gustafsson , K. , Sykes , B.W. , Verwilghen , D. , Palmers , K. , Sullivan , S. & van Galen , G. ( 2024 ) Trimethoprim- sulfonamide: a valid antimicro- bial treatment in foals? Journal of the American Veterinary Medical Association , 262 ( 6 ), 825 – 833 . Available from: https:// doi. org/ 10. 2460/ javma. 23. 09. 0536
Kamps , M. & Barakzai , S. ( 2024 ) Equine cheek tooth repulsion using small diameter repulsion pins: 20 cases . Equine Veterinary Journal , 56 ( 6 ), 1183 – 1192 . Available from: https:// doi. org/ 10. 1111/ evj. 14116
Means , K. , Hayden , L. , Kramer , J. , McCracken , M.J. , Reed , S.K. , Wilson , D.A. et al. ( 2024 ) Vertical pelvic movement asymmetry and lame- ness location in ipsilateral combined forelimb and hindlimb lame- ness cases . Equine Veterinary Journal . Available from: https:// doi. org/ 10. 1111/ evj. 14117 Epub ahead of print.
Olivo , G. , Zakia , L.S. , Ribeiro , M.G. , da Cunha , M.L.R.S. , Riboli , D.F.M. , Mello , P.L. et al. ( 2024 ) Methicillin- resistant staphylococcus spp. investigation in hospitalized horses and contacting personnel in a teaching veterinary hospital . Journal of Equine Veterinary Science , 134 , 105031 . Available from: https:// doi. org/ 10. 1016/j. jevs. 2024. 105031
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