590


|


TABLE 1 Results serum amyloid A 51 horses subdivision in three groups. No. of horses


Group


26 17 8


Negative Moderate High


Mean age (SD) 2.15 (1.08)


3.12 (1.54) 6.63 (6.70)


Mean SAA <3


24 535


SAA range 0–2


7–69 111–1160


RIEMERSMA ET AL.


Mean sum of weight 547 (229)


553 (196) 655 (270)


Note : Data of horses divided into three groups of post- operative serum amyloid A (SAA) depending on SAA value: Negative, Moderate and High, presenting number of horses, mean age and standard deviation, mean value and range of SAA, sum of weight of excised tissue and standard deviation for each of the three groups.


TABLE 2 Four horses with extreme SAA values. Breed


Standardbred Riding pony


Welsh Cob Warmblood


Age (years) 3


2


9 4


SAA pre- OP, mg/L 75 <3


<3 <3


SAA post- OP, mg/L 514


747


1110 1160


Remarks Possible orthopaedic injury


Violent character, unilateral cryptorchid


p.o. unilateral incisional infection Incisor removal, tetanus vaccination


Note : Additional data of four horses with extreme high values of p.o. serum amyloid A (SAA): presenting breed, age (in year), pre- operative SAA values, post- operative SAA values and some possible correlations.


FIGURE 4 Distribution of the sum of weight of excised vaginal process with content (Testis, Epididymus, Plexus pampiniformis, Ductus deferens) within the population of horses used in this study.


between p.o. SAA and age and removed tissue weight (Figures 5–7 ) showed a moderate but significantly ( p = 0.015) higher p.o. SAA in older horses. No statistical significance was shown between p.o. SAA and weight of removed tissue ( p = 0.531). A not surprising sig- nificant ( p = 0.002) correlation was found between age and weight of removed tissue (larger reproductive organs in mature horses). All other possible correlations did not prove statistically significant.


On the third p.o. day, the SAA data obtained through the closed inguinal approach demonstrated a markedly significant reduction ( P < 0.001) compared to the findings observed in four distinct field castration studies mentioned earlier (Table 3 ). This is true for each of the eight groups of horses described in the field castration studies (two groups in each study). Calculated Cohen ' s d ranged from 1.11 to 2.75 (Table 3 ); the value of ≥0.8 is considered a relevant finding.


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