USING EXOSOMES FOR RESOLVING MARE ENDOMETRITIS


Garlinghouse , S.E. & Burrill , M.J. ( 1999 ) Relationship of body condition score to completion rate during 160 km endurance races . Equine Veterinary Journal , 30 , 591 – 595 .


Gatti , S. , Bruno , S. , Deregibus , M.C. , Sordi , A. , Cantaluppi , V. & Tetta , C. ( 2011 ) Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia reperfusion induced acute and chronic kidney injury . Nephrology, Dialysis, Transplantation , 26 , 1474 – 1483 .


Gavalas , N.G. , Liontos , M. & Trachana , S.P. ( 2013 ) Angiogenesis- related pathways in the pathogenesis of ovarian cancer . International Journal of Molecular Sciences , 14 ( 8 ), 15885 – 15909 .


Gil- Sanchis , C. , Cervelló , I. , Khurana , S. , Faus , A. , Verfaillie , C. & Simón , C. ( 2015 ) Contribution of different bone marrow- derived cell types in endometrial regeneration using an irradiated murine model . Fertility and Sterility , 103 ( 6 ), 1596 – 1605 .


Govaere , J.L. , Hoogewijs , M.K. , De Schauwer , C. , De Vliegher , S. , Van Soom , A. , Duchateau , L. et al. ( 2014 ) Effect of artificial insem- ination protocol and dose of frozen/thawed stallion semen on pregnancy results in mares . Reproduction in Domestic Animals , 49 ( 3 ), 487 – 491 . Available from: https://doi.org/10.1111/ rda.12316


Hanlon , D.W. , Stevenson , M. , Evans , M.J. & Firth , E.C. ( 2012 ) Reproductive performance of Thoroughbred mares in the Waikato region of New Zealand: 2. Multivariable analyses and sources of variation at the mare, stallion and stud farm level . New Zealand Veterinary Journal , 60 , 335 – 343 .


Hurtgen , J.P. ( 2006 ) Pathogenesis and treatment of endometritis in the mare: a review . Theriogenology , 66 , 560 – 566 .


Jabbour , H.N. , Kelly , R.W. , Fraser , H.M. & Critchley , H.O. ( 2006 ) Endocrine regulation of menstruation . Endocrine Reviews , 27 , 17 – 46 .


Janowski , T. , Barańskıi , W. , Łukasik , K. , Skarżyński , D. , Rudowska , M. & Zduńczyk , S. ( 2013 ) Prevalence of subclinical endometritis in re- peat breeding cows and mRNA expression of tumor necrosis factor α and inducible nitric oxide synthase in the endometrium of repeat breeding cows with and without subclinical endometritis . Polish Journal of Veterinary Sciences , 16 ( 4 ), 693 – 699 .


Kenny , R.M. & Doig , P.A. ( 1986 ) Equine endometrial biopsy . In: Morrow , D.A. (Ed.) Current


Saunders , pp. 723 – 729 .


Koippallil , G.A.R. , Kishore , U. & Madan , T. ( 2017 ) Mesenchymal stem cells: a promising tool for targeted gene therapy of endometriosis . Regenerative Medicine , 12 , 69 – 76 .


Koot , Y.E. , Boomsma , C.M. , Eijkemans , M.J. , Lentjes , E.G. & Macklon , N.S. ( 2011 ) Recurrent pre- clinical pregnancy loss is unlikely to be a ‘cause’ of unexplained infertility . Human Reproduction , 26 ( 10 ), 2636 – 2641 .


Kotton , D.N. , Ma , B.Y. , Cardoso , W.V. , Sanderson , E.A. , Summer , R.S. , Williams , M.C. et al. ( 2001 ) Bone marrow- derived cells as progenitors of lung alveolar epithelium . Development , 128 ( 24 ), 5181 – 5188 .


Lange Consiglio , A. , Lazzari , B. , Perrini , C. , Pizzi , F. , Stella , A. & Cremonesi , F. ( 2018 ) MicroRNAs of equine amniotic mesenchymal cells- derived microvesicles and their involvement in anti- inflammatory process . Cell Transplantation , 27 , 45 – 54 .


Lange- Consiglio , A. , Tassan , S. , Corradetti , B. , Meucci , A. , Perego , R. , Bizzaro , D. et al. ( 2013 ) Investigating the potential of equine mesenchymal stem cells derived from amnion and bone marrow in equine tendon diseases treatment in vivo . Cytotherapy , 10 , 1016 – 1023 .


LeBlanc , M.M. ( 2010 ) Advances in the diagnosis and treatment of chronic infectious and post- mating- induced endometritis in the mare . Reproduction in Domestic Animals , 45 ( 2 ), 21 – 27 .


LeBlanc , M.M. & Causey , R.C. ( 2009 ) Clinical and subclinical endometri- tis in the mare: both threats to fertility . Reproduction in Domestic Animals , 44 ( 3 ), 10 – 22 .


therapy in Theriogenology . Philadelphia : WB


| 355


Li , J. , Zhang , Y.P. & Kirsner , R.S. ( 2003 ) Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix . Microscopy Research and Technique , 60 ( 1 ), 107 – 114 .


Maher , M.A. , Farghali , H.A.M. , Abdelnaby , E.A. & Emam , I.A. ( 2020 ) Gross anatomical, radiographic and Doppler sonographic approach to the infra- auricular parotid region in donkey ( Equus asinus ) . Journal of Equine Veterinary Science , 88 , 102968 .


Mambelli , L.I. , Winter , G.H.Z. , Kerkis , A. , Malschitzky , E. , Mattos , R.C. & Kerkis , I. ( 2013 ) A novel strategy of mesenchymal stem cells deliv- ery in the uterus of mares with endometrosis . Theriogenology , 79 , 744 – 750 .


Miyamoto , A. , Shirasuna , K. , Wijayagunawardane , M.P. , Watanabe , S. , Hayashi , M. , Yamamoto , D. et al. ( 2005 ) Blood flow: a key regu- latory component of corpus luteum function in the cow . Domestic Animal Endocrinology , 29 ( 2 ), 329 – 339 .


Morhayim , J. , Baroncelli , M. & van Leeuwen , J.P. ( 2014 ) Extracellular vesicles: specialized bone messengers . Archives of Biochemistry and Biophysics , 561 , 38 – 45 .


Morris , L.H.A. , McCue , P.M. & Aurich , C. ( 2020 ) Equine endometritis: a review of challenges and new approaches . Reproduction , 160 , 95 – 110 .


Reynolds , L.P. , Grazul- Bilska , A.T. & Redmer , D.A. ( 2002 ) Angiogenesis in the female


reproductive organs: pathological International Journal of Experimental Pathology , 83 ( 4 ), 151 – 163 .


Rink , B.E. , Beyer , T. , French , H.M. , Watson , E. , Aurich , C. & Donadeu , F.X. ( 2018 ) The fate of autologous endometrial mesenchymal stromal cells after application in the healthy equine uterus . Stem Cells and Development , 27 , 1046 – 1052 .


Sá , M.A.F. , Lima , T.F.G. , Morais , R.C.L. , Dutra , G.A. , Jesus , V.L.T. & Jacob , J.C.F. ( 2020 ) Acute endometritis induced by Escherichia coli in mares evaluated through color Doppler ultrasonogra- phy . Arquivo Brasileiro de Medicina Veterinária e Zootecnia , 72 , 1586 – 1598 .


Sabry , D. , Shamaa , A. , Amer , M. , El- Tookhy , O.S. , Abdallah , A. , Abd El Hassib , D.M. et al. ( 2018 ) The effect of mesenchymal stem cell de- rived microvesicles in repair of femoral chondral defects in dogs . Journal of Musculoskeletal Research , 21 , 1850006 .


Scoggin , C.F. ( 2016 ) Endometritis: non traditional therapies . The Veterinary Clinics of North America: Equine Practice , 32 , 499 – 511 .


Sikora , M. , Król , J. , Nowak , M. , Stefaniak , T. , Aubertsson , G. & Kozdrowski , R. ( 2015 ) The usefulness of uterine lavage and acute phase protein levels as a diagnostic tool for subclinical endometritis in Icelandic mares . Acta Veterinaria Scandinavica , 58 , 50 .


Silva , L.A. , Gastal , E.L. , Beg , M.A. & Ginther , O.J. ( 2005 ) Changes in vas- cular perfusion of the endometrium in association with changes in location of the embryonic vesicle in mares . Biology of Reproduction , 72 , 755 – 761 .


Suvarna , S.K. , Layton , C. & Bancroft , J.D. ( 2012 ) Bancroft ' s theory and practice of histological techniques , 7th edition . New York : Churchill Livingstone .


Tetta , C. , Ghigo , E. , Silengo , L. , Deregibus , M.C. & Camussi , G. ( 2013 ) Extracellular vesicles as an emerging mechanism of cell- to- cell communication . Endocrine , 44 , 11 – 19 .


Traub- Dargatz , J.L. , Salman , M.D. & Voss , J.L. ( 1991 ) Medical problems of adult horses, as ranked by equine practitioners . Journal of the American Veterinary Medical Association , 198 , 1745 – 1747 .


Troedsson , M.H.T. & Woodward , E.M. ( 2016 ) Our current understand- ing of the pathophysiology of equine endometritis with an em- phasis on breeding induced endometritis . Reproductive Biology , 16 , 8 – 12 .


Varadin , M. ( 1975 ) Endometritis, a common cause of infertility in mares . Journal of Reproduction and Fertility , 23 , 353 – 356 .


Woodward , E.M. & Troedsson , M.H.T. ( 2015 ) Inflammatory mech- anisms of endometritis . Journal of Equine Veterinary Science , 47 , 384 – 389 .


implications .


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62  |  Page 63  |  Page 64  |  Page 65  |  Page 66  |  Page 67  |  Page 68  |  Page 69  |  Page 70  |  Page 71  |  Page 72  |  Page 73  |  Page 74  |  Page 75  |  Page 76  |  Page 77  |  Page 78  |  Page 79  |  Page 80  |  Page 81  |  Page 82  |  Page 83  |  Page 84  |  Page 85  |  Page 86  |  Page 87  |  Page 88  |  Page 89  |  Page 90  |  Page 91  |  Page 92