Received: 6 April 2023 | Accepted: 17 October 2023 DOI: 10.1111/eve.13911


OR IG INA L A R T I C L E


Equine dental sinusitis—A statistical analysis of the effect of antibiotics on dental sinusitis following dental extraction


Camilla Vestergaard Lydiksen 1


1 Department of Veterinary Clinical Sciences, Section of Medicine and Surgery , University of Copenhagen , Taastrup , Denmark 2 Hestetandklinikken , Ringsted , Denmark 3 Department of Veterinary and Animal Sciences , University of Copenhagen , Frederiksberg C , Denmark


Correspondence: Casper Lindegaard Email: casper.lindegaard@sund.ku.dk


| Jonathan Ingerslev Christensen 1 | Jesper Grud Rosenmeier 2 | Dan Børge Jensen 3 | Casper Lindegaard 1


Summary Background : Antibiotic resistance is an increasing global threat to human and veterinary practices. The relevance and efficacy of antibiotic therapy in the treatment of various diseases has been poorly documented in the literature. One such disease is equine si- nusitis secondary to dental disease where dental extraction is most often combined with broad-spectrum antibiotic treatment. It, however, remains undocumented if antibiotic treatment reduces the risk of complication in horses where the diseased tooth is removed by extraction. Objectives : The aim of this study was to analyse the effects of perioperative antibiotics in horses with dental sinusitis treated by dental extraction with or without concurrent antibiotic treatment. Study design : Retrospective cohort study. Methods : Clinical records from horses presenting with nasal discharge between September 2016 and May 2022 were reviewed. Horses with sinusitis secondary to den- tal disease were identified, and data from clinical records were collected supplemented by online questionnaires. The final statistical model was built using logistic regression. Results : A total of 59 horses with dental sinusitis were included in the study. Following dental extraction, 62.5% (15/24) of horses that did receive perioperative antibiotics and 60% (21/35) of horses that did not receive perioperative antibiotics were successfully treated without the need for further treatment. The final model showed no significant difference on the probability of success ( p = 0.85) between treatment with and without antibiotics. Main limitations : The retrospective nature of this study may increase the risk of biases in relation to data collection and follow-up information and the limited number of individu- als available for the analysis. Conclusions : These findings indicate that the use of perioperative antibiotics does not influence the likelihood of complications or the probability of a successful outcome in horses with dental sinusitis undergoing dental extraction.


K E YWORDS horse , antibiotic , dental extraction , dental sinusitis , treatment


This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. © 2023 The Authors. Equine Veterinary Education published by John Wiley & Sons Ltd on behalf of EVJ Ltd.


Equine Vet Educ. 2024;36:357–365. aaep.org/wiley-redirect | 357

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